I don't know the answer, but here's my speculation based on what I do know.
First, it will plug in, so electrically it's compatible. I'm using the harness for the USA-SPEC changer to my Sat receiver, that's how compatible it is. No modifications.
Based on information I got from someone trying to get a Phatnoise going on his G35, the initial software he received, emulated the changer. When he plugged it in, it disabled the internal changer. So he got them to swap code so it emulated the SAT which he has no plans to use, and his CD changer became functional again.
When going into the Murano's diagnostics, it looks for a Sat receiver and a Changer, externally, to report back firmware revisions. That's on my Bose, you can check yours. With the radio off, turn on the ignition, hold the pause/mute button and keep spinning the volume knob (or is it the tuning knob, I've not been in my Murano for a week!) and spin it at least 20 clicks and you'll see the display go into a different mode. You can walk through the menus (you won't break anything, don't worry) and in there you should see what I'm talking about.
So based on this, my educated guess is there's an excellent chance it will work, and it may disable your internal CD player in the process.
But I've yet to hear from anyone who's tried it.
If you can find a local store that has one, tell them you'll buy it, if it works when it's plugged in. Or see what the return policy is from someone like Crutchfield or whoever....
Sorry I can't give you a definate yes or no!